Annual antimicrobial resistance in bacteria isolated from critical care

Kadriye Uzun 1, Hüseyin Güdücüoğlu 1, Mustafa Berktaş 1, Kürşat Uzun 2 *
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1 Yüzüncü Yıl Üniversitesi, Tıp Fakültesi, Mikrobiyoloji Anabilim Dalı, Van
2 Necmettin Erbakan Üniversitesi, Meram Tıp Fakültesi Göğüs Hastalıkları ve Yoğun Bakım Bilim Dalı, Konya
* Corresponding Author
EUR J BASIC MED SCI, Volume 4, Issue 3, pp. 58-65. https://doi.org/10.21601/ejbms/9222
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ABSTRACT

Critical care-acquired infections are the leading cause of mortality and morbidity despite advances in antimicrobial therapy, better supportive care modalities, and the use of a wide-range of preventive measures. The aim of this study is to evaluate antimicrobial resistance and susceptibility in bacteria isolated from critical care. 125 patients diagnosed infection were investigated in critical care unit. According to infectious status, 375 sample was taken from 125 patients (blood, BAL and urinary). Microorganisms were isolated in 254 patients. The most common cause of infections was acinetobacter spp. (22%), fungus (18.9%), staphylococcus spp (11.4%), and pseudomonas spp (15%). The susceptibility of acinetobacter spp against antimicrobial agents was colistin, tobramycin, tgycyclin and netilmycin. The susceptibility of pseudomonas spp against antimicrobial agents was colistin, amicacin, sulbactam-cefoperazone, piperacillin-tazobactam and meropenem. The susceptibility of klebsiella to antimicrobials was piperacillin-tazobactam, amicacin, sulbactam-cefoperazone and netilmycin. The susceptibility of E. coli to antimicrobials was amicacin, netilmycin, imipenem and sulbactam-cefoperazone. In this study, the most common isolated microorganisms were acinetobacter spp and the most effective drug was colistin. There is no colistin in Turkey.
Keywords: critical care, infection, antibiotic, resistance

CITATION

Uzun K, Güdücüoğlu H, Berktaş M, Uzun K. Annual antimicrobial resistance in bacteria isolated from critical care. Eur J Basic Med Sci. 2014;4(3):58-65. https://doi.org/10.21601/ejbms/9222

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