Matrix Metalloproteinases and Cancer

Müfide Öncel 1 *
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1 Beyhekim Devlet Hastanesi Biyokimya Laboratuvarı, Konya
* Corresponding Author
EUR J BASIC MED SCI, Volume 2, Issue 3, pp. 91-100. https://doi.org/10.21601/ejbms/9185
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ABSTRACT

Extracellular proteolysis involves in tissue homeostasis. However in cancer, accelerating proteolysis leads to unregulated tumor growth, inflammation, tissue invasion, and metastasis. Matrix metalloproteinases represent the most prominent subclass of proteinases associated with tumorigenesis. In recent years by means of technological developments the roles of matrix metalloproteinases in development of tumorigenesis have been evaluated. Thus, matrix metalloproteinases have become critical therapeutic and diagnostic targets due to their roles in tumoroginesis.
Keywords: matrix metalloproteinases, cancer, cancer therapy

CITATION

Öncel M. Matrix Metalloproteinases and Cancer. Eur J Basic Med Sci. 2012;2(3):91-100. https://doi.org/10.21601/ejbms/9185

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